Isobell Muirhead married Patrick Wybar (variously, Wyper).(3.29) They resided at Uphall, in West Lothian, variously, Linlithgowshire. They gave birth to: Agnes, born 1692; William, born 31 August 1701; Isaac, born 21 December 1703; Isobell, born 31 July 1706; Andrew, born 13 January 1709; and Agnes, born 04 July 1711.